Lotuvex is reader-supported. When you buy through links on our site, we may earn an affiliate commission at no extra cost to you.

Calcium, Vitamin D and K2 for Bone Health

Research summary · Updated 2026 · Not medical advice

Lotuvex is reader-supported. When you buy through links on our site, we may earn an affiliate commission at no extra cost to you.

Bone health is usually reduced to “take calcium.” The fuller picture involves three nutrients working together — and one of them is where most supplement routines fall short.

The three-part team

Calcium is the raw material. Vitamin D lets you absorb it. Vitamin K is involved in the proteins that direct calcium into bone. Taking calcium alone, with no attention to vitamin D status, is the most common mistake.

How much calcium, and food first

Most adults need around 1,000 mg of calcium daily, rising to 1,200 mg for women over 50 and everyone over 70. Dairy, fortified plant milks, tofu set with calcium, sardines and leafy greens all contribute — and food sources come with fewer concerns than large single doses from pills. The NIH Office of Dietary Supplements publishes a consumer sheet on calcium.

Where vitamin K2 fits

Vitamin K comes as K1 (leafy greens) and K2 (fermented foods, some animal products). K2 supplements — usually the MK-7 form — are marketed for directing calcium to bone rather than arteries. The mechanism is real, but human outcome evidence is still developing, so treat K2 as promising rather than proven. See the ODS sheet on vitamin K.

Fill the gap food leaves

Calcium + Vitamin D (e.g. Citracal, Nature Made)

  • Split doses — the body absorbs roughly 500 mg at a time
  • Citrate absorbs well without food; carbonate needs a meal
  • Aim to top up what your diet misses, not to duplicate it

Inexpensive · widely available

Check Price →
Promising, not proven

Vitamin K2 as MK-7 (e.g. NOW, Life Extension)

  • MK-7 is the longer-acting form used in most studies
  • Often paired with vitamin D3 in combination products
  • Not suitable if you take warfarin — see below

Optional add-on

Check Price →

Safety notes — the warfarin warning matters

Vitamin K directly interferes with warfarin. If you take warfarin or a similar anticoagulant, do not start a K2 supplement without talking to your doctor. For calcium, more is not better: very high supplemental intakes have been linked with kidney stones, and the sensible approach is to top up the gap rather than pile on. Vitamin D also has an upper limit — see our vitamin D guide.